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The mTOR pathway, serving as a critical metabolic regulator and mitophagy gatekeeper, integrates both metabolic and inflammatory signals to calibrate mitochondrial turnover and ROS productionkey mediators of ferroptosis induction by Erastin (6365)

Metal-based nanozymes Copper CuxO nanoparticle clusters containing phenylalanine have been shown to carry out multiple superoxide dismutase, catalase, glutathione peroxidase, and peroxidase-mimicking enzymes (Hao et al

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NAD+ supports energy production in cells, while glutathione helps neutralize the resulting oxidative byproducts